Dual PPARα/γ agonist aleglitazar confers stroke protection in a model of mild focal brain ischemia in mice

ABSTRACT: Peroxisome proliferator-activated receptors (PPARs) control the expression of genes involved in glucose homeostasis, lipid metabolism, inflammation, and cell differentiation. Here, we analyzed the effects of aleglitazar, a dual PPARα and PPARγ agonist with balanced affinity for either subt...

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Detalles Bibliográficos
Autores principales: Boujon, Valérie, Uhlemann, Ria, Wegner, Stephanie, Wright, Matthew B., Laufs, Ulrich, Endres, Matthias, Kronenberg, Golo, Gertz, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647083/
https://www.ncbi.nlm.nih.gov/pubmed/31147725
http://dx.doi.org/10.1007/s00109-019-01801-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647083/
https://www.ncbi.nlm.nih.gov/pubmed/31147725
http://dx.doi.org/10.1007/s00109-019-01801-0

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