A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers

BACKGROUND: The oral mucosa has an important role in maintaining barrier integrity at the gateway to the gastrointestinal and respiratory tracts. Smoking is a strong environmental risk factor for the common oral inflammatory disease periodontitis and oral cancer. Cigarette smoke affects gene methyla...

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Detalles Bibliográficos
Autores principales: Richter, Gesa M., Kruppa, Jochen, Munz, Matthias, Wiehe, Ricarda, Häsler, Robert, Franke, Andre, Martins, Orlando, Jockel-Schneider, Yvonne, Bruckmann, Corinna, Dommisch, Henrik, Schaefer, Arne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647091/
https://www.ncbi.nlm.nih.gov/pubmed/31331382
http://dx.doi.org/10.1186/s13148-019-0697-y

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