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Tenofovir alafenamide fumarate attenuates bleomycin-induced pulmonary fibrosis by upregulating the NS5ATP9 and TGF-β1/Smad3 signaling pathway

BACKGROUND: Pulmonary fibrosis is a progressive and irreversible disease for which therapeutic options are currently limited. A recent in vivo study showed that tenofovir, a nucleotide analogue reverse transcriptase inhibitor, had direct antifibrotic effects on skin and liver fibrosis. Another study...

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Detalles Bibliográficos
Autores principales:	Li, Lingxia, Zhao, Jing, Zhou, Li, Chen, Jie, Ma, Yuanyuan, Yu, Yanyan, Cheng, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647111/ https://www.ncbi.nlm.nih.gov/pubmed/31331325 http://dx.doi.org/10.1186/s12931-019-1102-2

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