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Assessment of the platelet-derived growth factor receptor alpha antibody olaratumab in a panel of patient-derived soft tissue sarcoma xenografts

BACKGROUND: Soft tissue sarcoma (STS) comprises a family of rare, heterogeneous tumors of mesenchymal origin. Single-agent doxorubicin remains the first-line standard-of-care treatment for advanced and inoperable STS, but response rates are only around 15%. In 2016, phase Ib/II clinical trial result...

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Detalles Bibliográficos
Autores principales:	Cornillie, Jasmien, Wozniak, Agnieszka, Van Renterghem, Britt, Van Winkel, Nathalie, Wellens, Jasmien, Gebreyohannes, Yemarshet K., Debiec-Rychter, Maria, Sciot, Raf, Hompes, Daphne, Schöffski, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647161/ https://www.ncbi.nlm.nih.gov/pubmed/31331295 http://dx.doi.org/10.1186/s12885-019-5872-1

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