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Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles

Alpha-synuclein (αS) is the major constituent of Lewy bodies and a pathogenic hallmark of all synucleinopathathies, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). All diseases are determined by αS aggregate deposition but can be separated into...

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Detalles Bibliográficos
Autores principales: Meade, Richard M., Fairlie, David P., Mason, Jody M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647174/
https://www.ncbi.nlm.nih.gov/pubmed/31331359
http://dx.doi.org/10.1186/s13024-019-0329-1

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