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Why are so many MLL lysine methyltransferases required for normal mammalian development?
The mixed lineage leukemia (MLL) family of proteins became known initially for the leukemia link of its founding member. Over the decades, the MLL family has been recognized as an important class of histone H3 lysine 4 (H3K4) methyltransferases that control key aspects of normal cell physiology and...
Autores principales: | Crump, Nicholas T., Milne, Thomas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647185/ https://www.ncbi.nlm.nih.gov/pubmed/31098676 http://dx.doi.org/10.1007/s00018-019-03143-z |
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