NEAT1 regulates neuroglial cell mediating Aβ clearance via the epigenetic regulation of endocytosis-related genes expression

The accumulation of intracellular β-amyloid peptide (Aβ) is important pathological characteristic of Alzheimer’s disease (AD). However, the exact underlying molecular mechanism remains to be elucidated. Here, we reported that Nuclear Paraspeckle Assembly Transcript 1 (NEAT1), a long n on-coding RNA,...

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Detalles Bibliográficos
Autores principales: Wang, Ziqiang, Zhao, Yiwan, Xu, Naihan, Zhang, Shikuan, Wang, Songmao, Mao, Yunhao, Zhu, Yuanchang, Li, Bing, Jiang, Yuyang, Tan, Ying, Xie, Weidong, Yang, Burton B., Zhang, Yaou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647258/
https://www.ncbi.nlm.nih.gov/pubmed/31006037
http://dx.doi.org/10.1007/s00018-019-03074-9

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