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Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIP(s)

BACKGROUND: Vitamin E δ-tocotrienol (VEDT), a vitamin E compound isolated from sources such as palm fruit and annatto beans, has been reported to have cancer chemopreventive and therapeutic effects. METHODS: We report a novel function of VEDT in augmenting tumor necrosis factor-related apoptosis-ind...

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Detalles Bibliográficos
Autores principales:	Francois, Rony A., Zhang, Anying, Husain, Kazim, Wang, Chen, Hutchinson, Sean, Kongnyuy, Michael, Batra, Surinder K., Coppola, Domenico, Sebti, Said M., Malafa, Mokenge P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647259/ https://www.ncbi.nlm.nih.gov/pubmed/31367187 http://dx.doi.org/10.1186/s12935-019-0876-0

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