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Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson’s disease

This article describes pathogenic concepts and factors, in particular glycolipid abnormalities, that create cell dysfunction and synaptic loss in neurodegenerative diseases. By phenocopying lysosomal storage disorders, such as Gaucher disease and related disorders, age- and dose-dependent changes in...

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Detalles Bibliográficos
Autores principales:	Hallett, Penelope J., Engelender, Simone, Isacson, Ole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647317/ https://www.ncbi.nlm.nih.gov/pubmed/31331333 http://dx.doi.org/10.1186/s12974-019-1532-2

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