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HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells

BACKGROUND: Sodium/iodide symporter (NIS)-mediated iodide uptake plays an important physiological role in regulating thyroid gland function, as well as in diagnosing and treating Graves’ disease and thyroid cancer. High-mobility group box 1 (HMGB1), a highly conserved nuclear protein, is a positive...

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Detalles Bibliográficos
Autores principales:	Chai, Wenwen, Ye, Fanghua, Zeng, Li, Li, Yanling, Yang, Liangchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647330/ https://www.ncbi.nlm.nih.gov/pubmed/31331356 http://dx.doi.org/10.1186/s13046-019-1328-3

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