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A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models
In this paper we introduce a novel method for prescribing terminal boundary conditions in one-dimensional arterial flow networks. This is carried out by coupling the terminal arterial vessel with a poro-elastic tube, representing the flow resistance offered by microcirculation. The performance of th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647433/ https://www.ncbi.nlm.nih.gov/pubmed/30900050 http://dx.doi.org/10.1007/s10237-019-01122-8 |
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author | Coccarelli, Alberto Prakash, Arul Nithiarasu, Perumal |
author_facet | Coccarelli, Alberto Prakash, Arul Nithiarasu, Perumal |
author_sort | Coccarelli, Alberto |
collection | PubMed |
description | In this paper we introduce a novel method for prescribing terminal boundary conditions in one-dimensional arterial flow networks. This is carried out by coupling the terminal arterial vessel with a poro-elastic tube, representing the flow resistance offered by microcirculation. The performance of the proposed porous media-based model has been investigated through several different numerical examples. First, we investigate model parameters that have a profound influence on the flow and pressure distributions of the system. The simulation results have been compared against the waveforms generated by three elements (RCR) Windkessel model. The proposed model is also integrated into a realistic arterial tree, and the results obtained have been compared against experimental data at different locations of the network. The accuracy and simplicity of the proposed model demonstrates that it can be an excellent alternative for the existing models. |
format | Online Article Text |
id | pubmed-6647433 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-66474332019-08-06 A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models Coccarelli, Alberto Prakash, Arul Nithiarasu, Perumal Biomech Model Mechanobiol Original Paper In this paper we introduce a novel method for prescribing terminal boundary conditions in one-dimensional arterial flow networks. This is carried out by coupling the terminal arterial vessel with a poro-elastic tube, representing the flow resistance offered by microcirculation. The performance of the proposed porous media-based model has been investigated through several different numerical examples. First, we investigate model parameters that have a profound influence on the flow and pressure distributions of the system. The simulation results have been compared against the waveforms generated by three elements (RCR) Windkessel model. The proposed model is also integrated into a realistic arterial tree, and the results obtained have been compared against experimental data at different locations of the network. The accuracy and simplicity of the proposed model demonstrates that it can be an excellent alternative for the existing models. Springer Berlin Heidelberg 2019-03-21 2019 /pmc/articles/PMC6647433/ /pubmed/30900050 http://dx.doi.org/10.1007/s10237-019-01122-8 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Paper Coccarelli, Alberto Prakash, Arul Nithiarasu, Perumal A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models |
title | A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models |
title_full | A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models |
title_fullStr | A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models |
title_full_unstemmed | A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models |
title_short | A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models |
title_sort | novel porous media-based approach to outflow boundary resistances of 1d arterial blood flow models |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647433/ https://www.ncbi.nlm.nih.gov/pubmed/30900050 http://dx.doi.org/10.1007/s10237-019-01122-8 |
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