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A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models

In this paper we introduce a novel method for prescribing terminal boundary conditions in one-dimensional arterial flow networks. This is carried out by coupling the terminal arterial vessel with a poro-elastic tube, representing the flow resistance offered by microcirculation. The performance of th...

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Detalles Bibliográficos
Autores principales: Coccarelli, Alberto, Prakash, Arul, Nithiarasu, Perumal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647433/
https://www.ncbi.nlm.nih.gov/pubmed/30900050
http://dx.doi.org/10.1007/s10237-019-01122-8
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author Coccarelli, Alberto
Prakash, Arul
Nithiarasu, Perumal
author_facet Coccarelli, Alberto
Prakash, Arul
Nithiarasu, Perumal
author_sort Coccarelli, Alberto
collection PubMed
description In this paper we introduce a novel method for prescribing terminal boundary conditions in one-dimensional arterial flow networks. This is carried out by coupling the terminal arterial vessel with a poro-elastic tube, representing the flow resistance offered by microcirculation. The performance of the proposed porous media-based model has been investigated through several different numerical examples. First, we investigate model parameters that have a profound influence on the flow and pressure distributions of the system. The simulation results have been compared against the waveforms generated by three elements (RCR) Windkessel model. The proposed model is also integrated into a realistic arterial tree, and the results obtained have been compared against experimental data at different locations of the network. The accuracy and simplicity of the proposed model demonstrates that it can be an excellent alternative for the existing models.
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spelling pubmed-66474332019-08-06 A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models Coccarelli, Alberto Prakash, Arul Nithiarasu, Perumal Biomech Model Mechanobiol Original Paper In this paper we introduce a novel method for prescribing terminal boundary conditions in one-dimensional arterial flow networks. This is carried out by coupling the terminal arterial vessel with a poro-elastic tube, representing the flow resistance offered by microcirculation. The performance of the proposed porous media-based model has been investigated through several different numerical examples. First, we investigate model parameters that have a profound influence on the flow and pressure distributions of the system. The simulation results have been compared against the waveforms generated by three elements (RCR) Windkessel model. The proposed model is also integrated into a realistic arterial tree, and the results obtained have been compared against experimental data at different locations of the network. The accuracy and simplicity of the proposed model demonstrates that it can be an excellent alternative for the existing models. Springer Berlin Heidelberg 2019-03-21 2019 /pmc/articles/PMC6647433/ /pubmed/30900050 http://dx.doi.org/10.1007/s10237-019-01122-8 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Coccarelli, Alberto
Prakash, Arul
Nithiarasu, Perumal
A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models
title A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models
title_full A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models
title_fullStr A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models
title_full_unstemmed A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models
title_short A novel porous media-based approach to outflow boundary resistances of 1D arterial blood flow models
title_sort novel porous media-based approach to outflow boundary resistances of 1d arterial blood flow models
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647433/
https://www.ncbi.nlm.nih.gov/pubmed/30900050
http://dx.doi.org/10.1007/s10237-019-01122-8
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