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Crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an XFEM interface damage model
Bulk properties of cortical bone have been well characterized experimentally, and potent toughening mechanisms, e.g., crack deflections, have been identified at the microscale. However, it is currently difficult to experimentally measure local damage properties and isolate their effect on the tissue...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647448/ https://www.ncbi.nlm.nih.gov/pubmed/30963356 http://dx.doi.org/10.1007/s10237-019-01142-4 |
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author | Gustafsson, Anna Wallin, Mathias Khayyeri, Hanifeh Isaksson, Hanna |
author_facet | Gustafsson, Anna Wallin, Mathias Khayyeri, Hanifeh Isaksson, Hanna |
author_sort | Gustafsson, Anna |
collection | PubMed |
description | Bulk properties of cortical bone have been well characterized experimentally, and potent toughening mechanisms, e.g., crack deflections, have been identified at the microscale. However, it is currently difficult to experimentally measure local damage properties and isolate their effect on the tissue fracture resistance. Instead, computer models can be used to analyze the impact of local characteristics and structures, but material parameters required in computer models are not well established. The aim of this study was therefore to identify the material parameters that are important for crack propagation in cortical bone and to elucidate what parameters need to be better defined experimentally. A comprehensive material parameter study was performed using an XFEM interface damage model in 2D to simulate crack propagation around an osteon at the microscale. The importance of 14 factors (material parameters) on four different outcome criteria (maximum force, fracture energy, crack length and crack trajectory) was evaluated using ANOVA for three different osteon orientations. The results identified factors related to the cement line to influence the crack propagation, where the interface strength was important for the ability to deflect cracks. Crack deflection was also favored by low interface stiffness. However, the cement line properties are not well determined experimentally and need to be better characterized. The matrix and osteon stiffness had no or low impact on the crack pattern. Furthermore, the results illustrated how reduced matrix toughness promoted crack penetration of the cement line. This effect is highly relevant for the understanding of the influence of aging on crack propagation and fracture resistance in cortical bone. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10237-019-01142-4) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-6647448 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-66474482019-08-06 Crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an XFEM interface damage model Gustafsson, Anna Wallin, Mathias Khayyeri, Hanifeh Isaksson, Hanna Biomech Model Mechanobiol Original Paper Bulk properties of cortical bone have been well characterized experimentally, and potent toughening mechanisms, e.g., crack deflections, have been identified at the microscale. However, it is currently difficult to experimentally measure local damage properties and isolate their effect on the tissue fracture resistance. Instead, computer models can be used to analyze the impact of local characteristics and structures, but material parameters required in computer models are not well established. The aim of this study was therefore to identify the material parameters that are important for crack propagation in cortical bone and to elucidate what parameters need to be better defined experimentally. A comprehensive material parameter study was performed using an XFEM interface damage model in 2D to simulate crack propagation around an osteon at the microscale. The importance of 14 factors (material parameters) on four different outcome criteria (maximum force, fracture energy, crack length and crack trajectory) was evaluated using ANOVA for three different osteon orientations. The results identified factors related to the cement line to influence the crack propagation, where the interface strength was important for the ability to deflect cracks. Crack deflection was also favored by low interface stiffness. However, the cement line properties are not well determined experimentally and need to be better characterized. The matrix and osteon stiffness had no or low impact on the crack pattern. Furthermore, the results illustrated how reduced matrix toughness promoted crack penetration of the cement line. This effect is highly relevant for the understanding of the influence of aging on crack propagation and fracture resistance in cortical bone. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10237-019-01142-4) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2019-04-08 2019 /pmc/articles/PMC6647448/ /pubmed/30963356 http://dx.doi.org/10.1007/s10237-019-01142-4 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Paper Gustafsson, Anna Wallin, Mathias Khayyeri, Hanifeh Isaksson, Hanna Crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an XFEM interface damage model |
title | Crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an XFEM interface damage model |
title_full | Crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an XFEM interface damage model |
title_fullStr | Crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an XFEM interface damage model |
title_full_unstemmed | Crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an XFEM interface damage model |
title_short | Crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an XFEM interface damage model |
title_sort | crack propagation in cortical bone is affected by the characteristics of the cement line: a parameter study using an xfem interface damage model |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647448/ https://www.ncbi.nlm.nih.gov/pubmed/30963356 http://dx.doi.org/10.1007/s10237-019-01142-4 |
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