Next-generation sequencing identifies novel mitochondrial variants in pituitary adenomas

PURPOSE: Disrupted mitochondrial functions and genetic variants of mitochondrial DNA (mtDNA) have been observed in different human neoplasms. Next-generation sequencing (NGS) can be used to detect even low heteroplasmy-level mtDNA variants. We aimed to investigate the mitochondrial genome in pituita...

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Detalles Bibliográficos
Autores principales: Németh, K., Darvasi, O., Likó, I., Szücs, N., Czirják, S., Reiniger, L., Szabó, B., Kurucz, P. A., Krokker, L., Igaz, P., Patócs, A., Butz, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647476/
https://www.ncbi.nlm.nih.gov/pubmed/30684245
http://dx.doi.org/10.1007/s40618-019-1005-6

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