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Osteopontin counters human immunodeficiency virus type 1–induced impairment of neurite growth through mammalian target of rapamycin and beta-integrin signaling pathways

Despite the fact that human immunodeficiency virus type 1 (HIV-1) does not enter or replicate in neurons, its infection of a subset of resident brain glia cells (microglia and astrocytes) induces via disparate mechanisms, dysregulation of glutamate metabolism, neurotoxicity, and inflammation. Antire...

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Detalles Bibliográficos
Autores principales: Calvez, Mathilde, Hseeh, George, Benzer, Simon, Brown, Amanda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647884/
https://www.ncbi.nlm.nih.gov/pubmed/30758811
http://dx.doi.org/10.1007/s13365-019-00729-y

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