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Osteopontin counters human immunodeficiency virus type 1–induced impairment of neurite growth through mammalian target of rapamycin and beta-integrin signaling pathways
Despite the fact that human immunodeficiency virus type 1 (HIV-1) does not enter or replicate in neurons, its infection of a subset of resident brain glia cells (microglia and astrocytes) induces via disparate mechanisms, dysregulation of glutamate metabolism, neurotoxicity, and inflammation. Antire...
Autores principales: | Calvez, Mathilde, Hseeh, George, Benzer, Simon, Brown, Amanda M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647884/ https://www.ncbi.nlm.nih.gov/pubmed/30758811 http://dx.doi.org/10.1007/s13365-019-00729-y |
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