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Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit

PURPOSE: We aimed to assess factors associated with therapy failure in patients with community-acquired pneumonia in the intensive care unit (ICU). METHODS: Electronic charts of patients with International Classification of Diseases, Ninth Revision, codes of pneumonia who were admitted to the ICU at...

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Detalles Bibliográficos
Autores principales: Hooten, Rorak, Luis Marquez, Jose, Goldlist, Kady, Urcis, Rafael, Adams, Matthew, Matthias, Kathryn R., Nix, David E., Al Mohajer, Mayar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647917/
https://www.ncbi.nlm.nih.gov/pubmed/31404133
http://dx.doi.org/10.4103/ajm.AJM_189_18
Descripción
Sumario:PURPOSE: We aimed to assess factors associated with therapy failure in patients with community-acquired pneumonia in the intensive care unit (ICU). METHODS: Electronic charts of patients with International Classification of Diseases, Ninth Revision, codes of pneumonia who were admitted to the ICU at a tertiary academic medical center in Southern Arizona were reviewed. RESULTS: Antipseudomonal coverage and anti-methicillin-resistant Staphylococcus aureus (MRSA) coverage were often prescribed (58.4% and 54.1%, respectively). Antipseudomonal coverage was rarely necessary as pseudomonal pneumonia was found in only one case (0.9%). Antipseudomonal and anti-MRSA coverage was not associated with improved outcomes. CONCLUSION: Overprescription of antibiotics in this population remains a significant problem. More work is needed to further limit unnecessary antibiotic use.