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Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit

PURPOSE: We aimed to assess factors associated with therapy failure in patients with community-acquired pneumonia in the intensive care unit (ICU). METHODS: Electronic charts of patients with International Classification of Diseases, Ninth Revision, codes of pneumonia who were admitted to the ICU at...

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Autores principales: Hooten, Rorak, Luis Marquez, Jose, Goldlist, Kady, Urcis, Rafael, Adams, Matthew, Matthias, Kathryn R., Nix, David E., Al Mohajer, Mayar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647917/
https://www.ncbi.nlm.nih.gov/pubmed/31404133
http://dx.doi.org/10.4103/ajm.AJM_189_18
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author Hooten, Rorak
Luis Marquez, Jose
Goldlist, Kady
Urcis, Rafael
Adams, Matthew
Matthias, Kathryn R.
Nix, David E.
Al Mohajer, Mayar
author_facet Hooten, Rorak
Luis Marquez, Jose
Goldlist, Kady
Urcis, Rafael
Adams, Matthew
Matthias, Kathryn R.
Nix, David E.
Al Mohajer, Mayar
author_sort Hooten, Rorak
collection PubMed
description PURPOSE: We aimed to assess factors associated with therapy failure in patients with community-acquired pneumonia in the intensive care unit (ICU). METHODS: Electronic charts of patients with International Classification of Diseases, Ninth Revision, codes of pneumonia who were admitted to the ICU at a tertiary academic medical center in Southern Arizona were reviewed. RESULTS: Antipseudomonal coverage and anti-methicillin-resistant Staphylococcus aureus (MRSA) coverage were often prescribed (58.4% and 54.1%, respectively). Antipseudomonal coverage was rarely necessary as pseudomonal pneumonia was found in only one case (0.9%). Antipseudomonal and anti-MRSA coverage was not associated with improved outcomes. CONCLUSION: Overprescription of antibiotics in this population remains a significant problem. More work is needed to further limit unnecessary antibiotic use.
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spelling pubmed-66479172019-08-09 Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit Hooten, Rorak Luis Marquez, Jose Goldlist, Kady Urcis, Rafael Adams, Matthew Matthias, Kathryn R. Nix, David E. Al Mohajer, Mayar Avicenna J Med Brief Report PURPOSE: We aimed to assess factors associated with therapy failure in patients with community-acquired pneumonia in the intensive care unit (ICU). METHODS: Electronic charts of patients with International Classification of Diseases, Ninth Revision, codes of pneumonia who were admitted to the ICU at a tertiary academic medical center in Southern Arizona were reviewed. RESULTS: Antipseudomonal coverage and anti-methicillin-resistant Staphylococcus aureus (MRSA) coverage were often prescribed (58.4% and 54.1%, respectively). Antipseudomonal coverage was rarely necessary as pseudomonal pneumonia was found in only one case (0.9%). Antipseudomonal and anti-MRSA coverage was not associated with improved outcomes. CONCLUSION: Overprescription of antibiotics in this population remains a significant problem. More work is needed to further limit unnecessary antibiotic use. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6647917/ /pubmed/31404133 http://dx.doi.org/10.4103/ajm.AJM_189_18 Text en Copyright: © 2019 Avicenna Journal of Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Brief Report
Hooten, Rorak
Luis Marquez, Jose
Goldlist, Kady
Urcis, Rafael
Adams, Matthew
Matthias, Kathryn R.
Nix, David E.
Al Mohajer, Mayar
Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit
title Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit
title_full Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit
title_fullStr Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit
title_full_unstemmed Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit
title_short Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit
title_sort overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647917/
https://www.ncbi.nlm.nih.gov/pubmed/31404133
http://dx.doi.org/10.4103/ajm.AJM_189_18
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