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Diacetyl Hexamethylene Diamine (CAHB) Exerts Pro-Apoptotic and Anti-Proliferative Function in Leukemic T Lymphocytes via Downregulating PI3K/Akt Signaling

BACKGROUND: T cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy caused by abnormal proliferation of immature T cell progenitors. Chemotherapy of T-ALL usually consists of induction, consolidation, and long-term maintenance. Diacetyl hexamethylene diamine (CAHB) is a n...

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Detalles Bibliográficos
Autores principales:	Hong, Ye, Zhang, Jia, Guo, Qunyi, Zhu, Min, Chen, Baoguo, Luo, Wenda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647926/ https://www.ncbi.nlm.nih.gov/pubmed/31301225 http://dx.doi.org/10.12659/MSM.915840

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