Cargando…

Serendipitous Formation of 2H-Pyrazolo[3,4-d]pyridazin-7(6H)-ones from 3-Arylsydnones

[Image: see text] Fused nitrogen heterocyclesnamely, pyrazolo[3,4-d]pyridazin-7(6H)-ones have been obtained by exploiting the 1,3-dipolar nature of N-arylsydnones, from hydrazones of 3-aryl-4-acetylsydnones via the Vilsmeier–Haack strategy. Facile intramolecular nucleophilic addition followed by CO(...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kumbar, Mahadev N., Shaikh, Saba Kauser J., Kamble, Ravindra R., Bayannavar, Praveen K., Kamble, Atulkumar A., Hunnur, Raveendra K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647958/ https://www.ncbi.nlm.nih.gov/pubmed/31459679 http://dx.doi.org/10.1021/acsomega.8b02013

Ejemplares similares

1-(4-Chlorophenyl)-1H-1,2,4-triazol-5(4H)-one
por: Kattimani, Pramod P., et al.
Publicado: (2014)

Design and Microwave Assisted Synthesis of Coumarin Derivatives as PDE Inhibitors
por: Kumbar, Mahadev N., et al.
Publicado: (2016)

Polyfunctional Nitriles in Organic Syntheses: A Novel Route to Aminopyrroles, Pyridazines and Pyrazolo[3,4-c]pyridazines
por: Al-Mousawi, Saleh M., et al.
Publicado: (2009)

3,4,7-Trimethyl-2-(4-methylphenyl)-2H-pyrazolo[3,4-d]pyridazin-5-ium thiocyanate
por: Abdel-Aziz, Hatem A., et al.
Publicado: (2010)

Introducing chirality in halogenated 3-arylsydnones and their corresponding 1-arylpyrazoles obtained by 1,3-dipolar cycloaddition
por: Popa, Marcel Mirel, et al.
Publicado: (2020)

Efficient synthesis of 1,3-diaryl-4-halo-1H-pyrazoles from 3-arylsydnones and 2-aryl-1,1-dihalo-1-alkenes
por: Yang, Yiwen, et al.
Publicado: (2011)

Synthesis, characterization and in vitro antimicrobial activity of novel fused pyrazolo[3,4-c]pyridazine, pyrazolo[3,4-d]pyrimidine, thieno[3,2-c]pyrazole and pyrazolo[3′,4′:4,5]thieno[2,3-d]pyrimidine derivatives
por: Abdel Reheim, Mohamed A. M., et al.
Publicado: (2017)

Correction to: Synthesis, characterization and in vitro antimicrobial activity of novel fused pyrazolo[3,4-c]pyridazine, pyrazolo[3,4-d]pyrimidine, thieno[3,2-c] pyrazole and pyrazolo[3′,4′:4,5]thieno[2,3-d]pyrimidine derivatives
por: Abdel Reheim, Mohamed A. M., et al.
Publicado: (2017)

3-Chloro-6-(1H-pyrazol-1-yl)pyridazine
por: Ather, Abdul Qayyum, et al.
Publicado: (2010)

Regioselectivity of 1,3-dipolar cycloadditions and antimicrobial activity of isoxazoline, pyrrolo[3,4-d]isoxazole-4,6-diones, pyrazolo[3,4-d]pyridazines and pyrazolo[1,5-a]pyrimidines
por: Zaki, Yasser Hassan, et al.
Publicado: (2016)

3-Iodo-1H-pyrazolo[3,4-b]pyridine
por: Huang, Ping-Hsin, et al.
Publicado: (2014)

6-Benzyloxy-2-phenylpyridazin-3(2H)-one
por: Ju, Zhi-Yu, et al.
Publicado: (2012)

4,5-Dichloro-2-methylpyridazin-3(2H)-one
por: Goh, Jia Hao, et al.
Publicado: (2009)

4-Benzyl-6-p-tolylpyridazin-3(2H)-one
por: Oubair, Ahmad, et al.
Publicado: (2009)

Synthesis and anti-HSV-1 evaluation of new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridines and 3H-pyrido[2,3-b]pyrazolo[3,4-h]-1,6-naphthyridines
por: Bernardino, Alice MR, et al.
Publicado: (2012)

Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-b]pyridazines for the Treatment of Human African Trypanosomiasis
por: Tear, Westley F., et al.
Publicado: (2019)

3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine
por: Ather, Abdul Qayyum, et al.
Publicado: (2010)

N-Phenyl-6-(1H-pyrazol-1-yl)pyridazin-3-amine
por: Ather, Abdul Qayyum, et al.
Publicado: (2010)

3-(Piperidin-1-yl)-6-(1H-pyrazol-1-yl)pyridazine
por: Ather, Abdul Qayyum, et al.
Publicado: (2010)

Synthesis and Antimicrobial Screening of Pyrazolo-3-Aryl Quinazolin-4(3H)ones
por: Deshmukh, M. B., et al.
Publicado: (2010)

1,4-Dimethyl-3-phenyl-3H-pyrazolo[3,4-c]isoquinolin-5(4H)-one
por: Meneghetti, Fiorella, et al.
Publicado: (2008)

Discovery of a High Affinity Adenosine A(1)/A(3) Receptor Antagonist with a Novel 7-Amino-pyrazolo[3,4-d]pyridazine Scaffold
por: Suchankova, Anna, et al.
Publicado: (2022)

1H-Pyrazolo[4,3-g]benzothiazol-7-amine
por: Camacho, José R., et al.
Publicado: (2009)

4-Benzylsulfanyl-1H-pyrazolo[3,4-d]pyrimidine
por: El Fal, Mohammed, et al.
Publicado: (2013)

1H-Pyrazolo[3,4-b]pyridines: Synthesis and Biomedical Applications
por: Donaire-Arias, Ana, et al.
Publicado: (2022)

6-Methyl-2-phenyl-4,5-dihydropyridazin-3(2H)-one
por: Sekkak, Hanan, et al.
Publicado: (2011)

Organometallic 3-(1H-Benzimidazol-2-yl)-1H-pyrazolo[3,4-b]pyridines as Potential Anticancer Agents
por: Stepanenko, Iryna N., et al.
Publicado: (2011)

Diclomezine: 6-(3,5-dichloro-4-methylphenyl)pyridazin-3(2H)-one
por: Kim, Hyunjee, et al.
Publicado: (2010)

3-Methyl-1,4-diphenyl-1H-pyrazolo[3,4-b]quinoline
por: Szlachcic, Paweł, et al.
Publicado: (2010)

5-[(tert-Butyldiphenylsilyloxy)methyl]pyridazin-3(2H)-one
por: Costas-Lago, María Carmen, et al.
Publicado: (2013)

4-[(tert-Butyldiphenylsilyloxy)methyl]pyridazin-3(2H)-one
por: Costas-Lago, María Carmen, et al.
Publicado: (2013)

Synthesis and Antifungal Activity of 5-Chloro-6-Phenyl-pyridazin-3(2H)-one Derivatives
por: Wu, Jian, et al.
Publicado: (2009)

3,4,6-Trimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine
por: Hamri, Salha, et al.
Publicado: (2010)

1,3-Diphenyl-8-trifluoromethyl-1H-pyrazolo[3,4-b]quinoline
por: Szlachcic, Paweł, et al.
Publicado: (2012)

Nanoparticles of a Pyrazolo-Pyridazine Derivative as Potential EGFR and CDK-2 Inhibitors: Design, Structure Determination, Anticancer Evaluation and In Silico Studies
por: Hashem, Heba E., et al.
Publicado: (2023)

Some Other Serendipitous Discoveries in Dermatology
por: Sharma, Yugal K, et al.
Publicado: (2016)

N-(2-Methylphenyl)-6-(1H-pyrazol-1-yl)pyridazin-3-amine
por: Ather, Abdul Qayyum, et al.
Publicado: (2009)

3-Hydroxy-1-[(morpholin-4-yl)methyl]pyridazin-6(1H)-one
por: Santhi, P. R., et al.
Publicado: (2013)

Synthesis, Characterization and Solubility Determination of 6-Phenyl-pyridazin-3(2H)-one in Different Pharmaceutical Solvents
por: Shakeel, Faiyaz, et al.
Publicado: (2019)

Crystal structure of 4-allylsulfanyl-1H-pyrazolo[3,4-d]pyrimidine
por: El Fal, Mohammed, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_tnvp1satefd3qj613ft6mdprnc