Cargando…
Optimized Stepwise Synthesis of the API Liraglutide Using BAL Resin and Pseudoprolines
[Image: see text] The number of peptide-based active pharmaceutical ingredients (APIs) has increased enormously in recent years. Furthermore, the emerging new peptide drug candidates are more complex and larger. For the industrial solid-phase synthesis of C-carboxylic acid peptides, the two main res...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648002/ https://www.ncbi.nlm.nih.gov/pubmed/31459957 http://dx.doi.org/10.1021/acsomega.9b00974 |