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Benzotriazole as an Efficient Ligand in Cu-Catalyzed Glaser Reaction
[Image: see text] Benzotriazole has been established as an efficient ligand in Cu-catalyzed cross-coupling of terminal alkynes to form 1,3-dialkynes using CuI as the catalyst and K(2)CO(3) as the base at room temperature in an open round-bottom flask. The established protocol has the following notab...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648008/ https://www.ncbi.nlm.nih.gov/pubmed/31459480 http://dx.doi.org/10.1021/acsomega.8b03410 |
Sumario: | [Image: see text] Benzotriazole has been established as an efficient ligand in Cu-catalyzed cross-coupling of terminal alkynes to form 1,3-dialkynes using CuI as the catalyst and K(2)CO(3) as the base at room temperature in an open round-bottom flask. The established protocol has the following notable advantages: simple to handle, easy work-up, mild reaction condition, high substrate scope, requirement of less quantity of ligand and also Cu-catalyst, less expensive, and high reaction yield. |
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