Cargando…

Guide to the Assessment of Mature Liver Gene Expression in Stem Cell-Derived Hepatocytes

Differentiation of stem cells to hepatocyte-like cells (HLCs) holds great promise for basic research, drug and toxicological investigations, and clinical applications. There are currently no protocols for the production of HLCs from stem cells, such as embryonic stem cells or induced pluripotent ste...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zabulica, Mihaela, Srinivasan, Raghuraman C., Vosough, Massoud, Hammarstedt, Christina, Wu, Tingting, Gramignoli, Roberto, Ellis, Ewa, Kannisto, Kristina, Collin de l'Hortet, Alexandra, Takeishi, Kazuki, Soto-Gutierrez, Alejandro, Strom, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2019
Materias:	Original Research Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648222/ https://www.ncbi.nlm.nih.gov/pubmed/31122128 http://dx.doi.org/10.1089/scd.2019.0064

Ejemplares similares

Gene Editing Correction of a Urea Cycle Defect in Organoid Stem Cell Derived Hepatocyte-like Cells
por: Zabulica, Mihaela, et al.
Publicado: (2021)

Applying hydrodynamic pressure to efficiently generate induced pluripotent stem cells via reprogramming of centenarian skin fibroblasts
por: Vosough, Massoud, et al.
Publicado: (2019)

SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids
por: Tobita, Takamasa, et al.
Publicado: (2016)

Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes
por: Zabulica, Mihaela, et al.
Publicado: (2021)

EGFR: A Master Piece in G1/S Phase Transition of Liver Regeneration
por: Collin de l'Hortet, Alexandra, et al.
Publicado: (2012)

Effects of Cryogenic Storage on Human Amnion Epithelial Cells
por: Srinivasan, Raghuraman C., et al.
Publicado: (2020)

Procurement and Evaluation of Hepatocytes for Transplantation From Neonatal Donors After Circulatory Death
por: Bluhme, Emil, et al.
Publicado: (2022)

Tissue-Specific Microparticles Improve Organoid Microenvironment for Efficient Maturation of Pluripotent Stem-Cell-Derived Hepatocytes
por: Zahmatkesh, Ensieh, et al.
Publicado: (2021)

Liver‐enriched transcription factor expression relates to chronic hepatic failure in humans
por: Guzman‐Lepe, Jorge, et al.
Publicado: (2018)

Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes
por: Gramignoli, Roberto, et al.
Publicado: (2022)

Extraembryonic Mesenchymal Stromal/Stem Cells in Liver Diseases: A Critical Revision of Promising Advanced Therapy Medicinal Products
por: Shahrbaf, Mohammad Amin, et al.
Publicado: (2022)

Biofabrication of synthetic human liver tissue with advanced programmable functions
por: Florentino, Rodrigo M., et al.
Publicado: (2022)

In Vitro Generated Hepatocyte-Like Cells: A Novel Tool in Regenerative Medicine and Drug Discovery
por: Zakikhan, Kobra, et al.
Publicado: (2017)

Amniotic Membrane and Its Derivatives: Novel Therapeutic Modalities in Liver Disorders
por: Arki, Mandana Kazem, et al.
Publicado: (2023)

Exogenous alpha 1-antitrypsin down-regulates SERPINA1 expression
por: Karadagi, Ahmad, et al.
Publicado: (2017)

Galactosylation of rat natural scaffold for MSC differentiation into hepatocyte-like cells: A comparative analysis of 2D vs. 3D cell culture techniques
por: Vazirzadeh, Masoud, et al.
Publicado: (2023)

Umbilical Cord Blood-Derived Monocytes as A Reliable Source of Functional Macrophages for Biomedical Research
por: Torabi, Shukoofeh, et al.
Publicado: (2023)

Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases
por: Holmgren, Gustav, et al.
Publicado: (2020)

Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans
por: Florentino, Rodrigo M., et al.
Publicado: (2020)

Conditioned Media Derived from Human Adipose Tissue Mesenchymal Stromal Cells Improves Primary Hepatocyte Maintenance
por: Azhdari Tafti, Zahra, et al.
Publicado: (2018)

Conditioned Media Derived from Human Adipose Tissue Mesenchymal Stromal Cells Improves Primary Hepatocyte Maintenance
por: Azhdari Tafti, Zahra, et al.
Publicado: (2021)

Human Amnion Epithelial Cells Impair T Cell Proliferation: The Role of HLA-G and HLA-E Molecules
por: Morandi, Fabio, et al.
Publicado: (2020)

Rat-Derived Amniotic Epithelial Cells Differentiate into Mature Hepatocytes In Vivo with No Evidence of Cell Fusion
por: Marongiu, Michela, et al.
Publicado: (2015)

Novel Gene-Correction-Based Therapeutic Modalities for Monogenic Liver Disorders
por: Ghasemzad, Mahsa, et al.
Publicado: (2022)

Tissue Engineering in Liver Regenerative Medicine: Insights into Novel Translational Technologies
por: Heydari, Zahra, et al.
Publicado: (2020)

Brain integrity is altered by hepatic APOE ε4 in humanized-liver mice
por: Giannisis, Andreas, et al.
Publicado: (2022)

De Novo Donor‐Specific HLA Antibody Formation in Two Patients With Crigler‐Najjar Syndrome Type I Following Human Hepatocyte Transplantation With Partial Hepatectomy Preconditioning
por: Jorns, C., et al.
Publicado: (2015)

The ploidy-conveyor of mature hepatocytes as a source of genetic variation
por: Duncan, Andrew W., et al.
Publicado: (2010)

IL‐8 induces transdifferentiation of mature hepatocytes toward the cholangiocyte phenotype
por: Sasaki, Tokio, et al.
Publicado: (2019)

Genotoxic effects of 2-acetylaminofluorene on rat and human hepatocytes.
por: Strom, S C, et al.
Publicado: (1983)

Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix—A Comparative Analysis of Bioartificial Liver Microenvironments
por: Wang, Bo, et al.
Publicado: (2016)

Maturation of Induced Pluripotent Stem Cell Derived Hepatocytes by 3D-Culture
por: Gieseck III, Richard L., et al.
Publicado: (2014)

Contribution of Mature Hepatocytes to Biliary Regeneration in Rats with Acute and Chronic Biliary Injury
por: Chen, Ya-Hui, et al.
Publicado: (2015)

Induction and Maturation of Hepatocyte-Like Cells In Vitro: Focus on Technological Advances and Challenges
por: Xie, Ye, et al.
Publicado: (2021)

In-organoid single-cell CRISPR screening reveals determinants of hepatocyte differentiation and maturation
por: Liang, Junbo, et al.
Publicado: (2023)

Critical signaling pathways governing hepatocellular carcinoma behavior; small molecule-based approaches
por: Farzaneh, Zahra, et al.
Publicado: (2021)

The First Live-Cell Based Product in The Iranian Drug List; ReColorCell®
por: Shahrbaf, Mohammad Amin, et al.
Publicado: (2023)

Hepatocyte Differentiation from iPSCs or MSCs in Decellularized Liver Scaffold: Cell–ECM Adhesion, Spatial Distribution, and Hepatocyte Maturation Profile
por: Antarianto, Radiana Dhewayani, et al.
Publicado: (2022)

Food-Derived β-Carboline Alkaloids Ameliorate Lipid Droplet Accumulation in Human Hepatocytes
por: Dibwe, Dya Fita, et al.
Publicado: (2022)

Chenodeoxycholic Acid Modulates Bile Acid Synthesis Independent of Fibroblast Growth Factor 19 in Primary Human Hepatocytes
por: Johansson, Helene, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_m6k626bm2dgoh3ivd6qvetonoc