Identification of New Mono/Dihydroxynaphthoquinone as Lead Agents That Inhibit the Growth of Refractive and Triple-Negative Breast Cancer Cell Lines

[Image: see text] Human epidermal growth factor receptor 2 (HER2) is overexpressed in nearly 20–30% of breast cancers and is associated with metastasis resulting in poor patient survival and high recurrence. The dual EGFR/HER2 kinase inhibitor lapatinib has shown promising clinical results, but its...

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Detalles Bibliográficos
Autores principales: Schroeder, Richard, Sfondouris, Mary, Goyal, Navneet, Komati, Rajesh, Weerathunga, Achira, Gettridge, Cory, Stevens, Cheryl L. Klein, Jones, Frank E., Sridhar, Jayalakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648266/
https://www.ncbi.nlm.nih.gov/pubmed/31460159
http://dx.doi.org/10.1021/acsomega.9b00929

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