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Synthesis and Evaluation of Dibenzothiophene Analogues as Pin1 Inhibitors for Cervical Cancer Therapy

[Image: see text] The peptidyl-prolyl isomerase Pin1 is correlated with the progression of cervical cancer via regulating numerous oncogenic and tumor suppressor pathways. p65 is a crucial regulator of tumorigenesis that is regulated by Pin1, and p65 signaling suppression can enhance the antitumor e...

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Detalles Bibliográficos
Autores principales:	Wu, Ke-Jia, Liu, Xie, Wong, Suk-Yu, Zhou, Yuyang, Ma, Dik-Lung, Leung, Chung-Hang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648297/ https://www.ncbi.nlm.nih.gov/pubmed/31460012 http://dx.doi.org/10.1021/acsomega.9b00281

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