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CarD and RbpA modify the kinetics of initial transcription and slow promoter escape of the Mycobacterium tuberculosis RNA polymerase

The pathogen Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, enacts unique transcriptional regulatory mechanisms when subjected to host-derived stresses. Initiation of transcription by the Mycobacterial RNA polymerase (RNAP) has previously been shown to exhibit different open...

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Detalles Bibliográficos
Autores principales: Jensen, Drake, Manzano, Ana Ruiz, Rammohan, Jayan, Stallings, Christina L, Galburt, Eric A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648326/
https://www.ncbi.nlm.nih.gov/pubmed/31127308
http://dx.doi.org/10.1093/nar/gkz449

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