Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins

Rearrangement of the 1q12 pericentromeric heterochromatin and subsequent amplification of the 1q arm is commonly associated with cancer development and progression and may result from epigenetic deregulation. In many premalignant and malignant cells, loss of 1q12 satellite DNA methylation causes the...

Descripción completa

Detalles Bibliográficos
Autores principales: Traynor, Sofie, Møllegaard, Niels Erik, Jørgensen, Mikkel G, Brückmann, Nadine H, Pedersen, Christina B, Terp, Mikkel G, Johansen, Simone, Dejardin, Jerome, Ditzel, Henrik J, Gjerstorff, Morten F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648343/
https://www.ncbi.nlm.nih.gov/pubmed/31114908
http://dx.doi.org/10.1093/nar/gkz396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648343/
https://www.ncbi.nlm.nih.gov/pubmed/31114908
http://dx.doi.org/10.1093/nar/gkz396

Ejemplares similares