Cargando…

In vivo analysis of influenza A mRNA secondary structures identifies critical regulatory motifs

The influenza A virus (IAV) is a continuous health threat to humans as well as animals due to its recurring epidemics and pandemics. The IAV genome is segmented and the eight negative-sense viral RNAs (vRNAs) are transcribed into positive sense complementary RNAs (cRNAs) and viral messenger RNAs (mR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simon, Lisa Marie, Morandi, Edoardo, Luganini, Anna, Gribaudo, Giorgio, Martinez-Sobrido, Luis, Turner, Douglas H, Oliviero, Salvatore, Incarnato, Danny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648356/ https://www.ncbi.nlm.nih.gov/pubmed/31053845 http://dx.doi.org/10.1093/nar/gkz318

Ejemplares similares

In vivo probing of nascent RNA structures reveals principles of cotranscriptional folding
por: Incarnato, Danny, et al.
Publicado: (2017)

Contrasting silencing mechanisms of the same target mRNA by two regulatory RNAs in Escherichia coli
por: Lalaouna, David, et al.
Publicado: (2018)

A transient α-helix in the N-terminal RNA recognition motif of polypyrimidine tract binding protein senses RNA secondary structure
por: Maris, Christophe, et al.
Publicado: (2020)

Position-dependent sequence motif preferences of SpCas9 are largely determined by scaffold-complementary spacer motifs
por: Huszár, Krisztina, et al.
Publicado: (2023)

TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway
por: Choudhury, Nila Roy, et al.
Publicado: (2022)

YB-1 unwinds mRNA secondary structures in vitro and negatively regulates stress granule assembly in HeLa cells
por: Budkina, Karina, et al.
Publicado: (2021)

High-throughput single-base resolution mapping of RNA 2΄-O-methylated residues
por: Incarnato, Danny, et al.
Publicado: (2017)

NMR-derived secondary structure of the full-length Ox40 mRNA 3′UTR and its multivalent binding to the immunoregulatory RBP Roquin
por: Tants, Jan-Niklas, et al.
Publicado: (2022)

Identification of conserved, primary sequence motifs that direct retrovirus RNA fate
por: Singh, Gatikrushna, et al.
Publicado: (2018)

hnRNPK recognition of the B motif of Xist and other biological RNAs
por: Nakamoto, Meagan Y, et al.
Publicado: (2020)

LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA
por: Cruz-Gallardo, Isabel, et al.
Publicado: (2019)

De novo discovery of structural motifs in RNA 3D structures through clustering
por: Ge, Ping, et al.
Publicado: (2018)

G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum
por: Dumetz, Franck, et al.
Publicado: (2021)

Control of mRNA decapping by autoinhibition
por: Paquette, David R, et al.
Publicado: (2018)

Human OAS1 activation is highly dependent on both RNA sequence and context of activating RNA motifs
por: Schwartz, Samantha L, et al.
Publicado: (2020)

Determinants of the temperature adaptation of mRNA degradation
por: Jaquet, Vincent, et al.
Publicado: (2022)

High-affinity RNA targets of the Survival Motor Neuron protein reveal diverse preferences for sequence and structural motifs
por: Ottesen, Eric W, et al.
Publicado: (2018)

G-quadruplexes offer a conserved structural motif for NONO recruitment to NEAT1 architectural lncRNA
por: Simko, Eric A J, et al.
Publicado: (2020)

Human histone pre-mRNA assembles histone or canonical mRNA-processing complexes by overlapping 3′-end sequence elements
por: Ielasi, Francesco S, et al.
Publicado: (2022)

When translation elongation is impaired, the mRNA is uniformly destabilized by the RNA degradosome, while the concentration of mRNA is altered along the molecule
por: Duviau, Marie-Pierre, et al.
Publicado: (2023)

Alu insertion variants alter mRNA splicing
por: Payer, Lindsay M, et al.
Publicado: (2019)

The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21
por: Torres-Fernández, Lucia A, et al.
Publicado: (2019)

Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer
por: Gupta, Kushol, et al.
Publicado: (2021)

Structural characterization of maternally expressed gene 3 RNA reveals conserved motifs and potential sites of interaction with polycomb repressive complex 2
por: Sherpa, Chringma, et al.
Publicado: (2018)

Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal
por: Glasser, Eliezra, et al.
Publicado: (2022)

ALYREF mainly binds to the 5′ and the 3′ regions of the mRNA in vivo
por: Shi, Min, et al.
Publicado: (2017)

Structure and dynamics of the quaternary hunchback mRNA translation repression complex
por: Macošek, Jakub, et al.
Publicado: (2021)

Transcription feedback dynamics in the wake of cytoplasmic mRNA degradation shutdown
por: Chappleboim, Alon, et al.
Publicado: (2022)

Dimerization of an umbravirus RNA genome activates subgenomic mRNA transcription
por: Chkuaseli, Tamari, et al.
Publicado: (2023)

The intrinsically disordered N-terminal arm of the brome mosaic virus coat protein specifically recognizes the RNA motif that directs the initiation of viral RNA replication
por: Jacobs, Alexander, et al.
Publicado: (2018)

Unfolding of an RNA G-quadruplex motif in the negative strand genome of porcine reproductive and respiratory syndrome virus by host and viral helicases to promote viral replication
por: Fang, Puxian, et al.
Publicado: (2023)

Characterization of zygotic genome activation-dependent maternal mRNA clearance in mouse
por: Sha, Qian-Qian, et al.
Publicado: (2020)

Regulation of AR mRNA translation in response to acute AR pathway inhibition
por: Somasekharan, Syam Prakash, et al.
Publicado: (2021)

Dynamic m(6)A modification regulates local translation of mRNA in axons
por: Yu, Jun, et al.
Publicado: (2018)

Direct role for the Drosophila GIGYF protein in 4EHP-mediated mRNA repression
por: Ruscica, Vincenzo, et al.
Publicado: (2019)

Pseudouridine-mediated translation control of mRNA by methionine aminoacyl tRNA synthetase
por: Levi, Ofri, et al.
Publicado: (2020)

Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA
por: Powers, Kyle T, et al.
Publicado: (2021)

SOX9 has distinct regulatory roles in alternative splicing and transcription
por: Girardot, Michael, et al.
Publicado: (2018)

Translation initiation of alphavirus mRNA reveals new insights into the topology of the 48S initiation complex
por: Toribio, René, et al.
Publicado: (2018)

A combinatorial code for mRNA 3′-UTR-mediated translational control in the mouse oocyte
por: Dai, Xing-Xing, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9bj8ts53res8f0f99nscovl935