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A tunable assay for modulators of genome-destabilizing DNA structures

Regions of genomic instability are not random and often co-localize with DNA sequences that can adopt alternative DNA structures (i.e. non-B DNA, such as H-DNA). Non-B DNA-forming sequences are highly enriched at translocation breakpoints in human cancer genomes, representing an endogenous source of...

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Detalles Bibliográficos
Autores principales:	del Mundo, Imee M A, Cho, Eun Jeong, Dalby, Kevin N, Vasquez, Karen M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648359/ https://www.ncbi.nlm.nih.gov/pubmed/30949695 http://dx.doi.org/10.1093/nar/gkz237

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