Breast cancer in patients with germline TP53 pathogenic variants have typical tumour characteristics: the Cohort study of TP53 carrier early onset breast cancer (COPE study)

Germline TP53 pathogenic variants are rare but associated with a high risk of cancer; they are often identified in the context of clinically diagnosed Li–Fraumeni syndrome predisposing to a range of young onset cancers including sarcomas and breast cancer. The study aim was to conduct a detailed mor...

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Detalles Bibliográficos
Autores principales: Packwood, Kate, Martland, Guy, Sommerlad, Matthew, Shaw, Emily, Moutasim, Karwan, Thomas, Gareth, Bateman, Adrian C, Jones, Louise, Haywood, Linda, Evans, D Gareth, Birch, Jillian M, Alsalmi, Ohud A, Henderson, Alex, Poplawski, Nicola, Eccles, Diana M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648388/
https://www.ncbi.nlm.nih.gov/pubmed/31041842
http://dx.doi.org/10.1002/cjp2.133

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