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Downconversion Luminescence-Based Nanosensor for Label-Free Detection of Explosives

[Image: see text] We report a selective and sensitive nanosensor probe based on polyethylenimine (PEI)-capped downconverting nanophosphors β-NaYF(4):Gd(3+),Tb(3+)@PEI for the detection of 2,4,6-trinitrotoluene (TNT), both in water and buffer media. These downconverting phosphors were synthesized via...

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Autores principales: Malik, Monika, Padhye, Preeti, Poddar, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648544/
https://www.ncbi.nlm.nih.gov/pubmed/31459633
http://dx.doi.org/10.1021/acsomega.8b03491
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author Malik, Monika
Padhye, Preeti
Poddar, Pankaj
author_facet Malik, Monika
Padhye, Preeti
Poddar, Pankaj
author_sort Malik, Monika
collection PubMed
description [Image: see text] We report a selective and sensitive nanosensor probe based on polyethylenimine (PEI)-capped downconverting nanophosphors β-NaYF(4):Gd(3+),Tb(3+)@PEI for the detection of 2,4,6-trinitrotoluene (TNT), both in water and buffer media. These downconverting phosphors were synthesized via a hydrothermal route and are known to show excellent chemical, thermal, and photostability. They emit sharp emission peaks centered at ∼488, 544, 584, and 619 nm, among which the peak at ∼544 nm was remarkably quenched (∼90%) by the addition of TNT without giving any new emission peak. The sensing mechanism is based on the formation of a Meisenheimer complex between the electron-rich amine-functionalized β-NaYF(4):Gd(3+),Tb(3+) nanophosphors and electron-deficient TNT molecule, which was prominently visualized by the change in the color of the solution from whitish to brownish yellow, enabling visual detection, followed by luminescence resonance energy transfer between the nanophosphors and the complex. A linear range for TNT detection was obtained from 0.1 to 300 μM with a limit of detection as low as 119.9 nM. This method displayed excellent selectivity toward TNT over other nitroaromatic compounds, which had no influence on the detection. Moreover, various other classes of analytes, viz., amino acids, pesticides, and sugars, did not quench the luminescence intensity of the nanophosphors. This developed nanosensor probe possesses high, stable fluorescence brightness and capability for the selective and sensitive on-site recognition of TNT molecules in aqueous media, avoiding complicated strategies and instruments. Thus, this work promises to pave ways to many applications in the detection of ultratrace analytes.
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spelling pubmed-66485442019-08-27 Downconversion Luminescence-Based Nanosensor for Label-Free Detection of Explosives Malik, Monika Padhye, Preeti Poddar, Pankaj ACS Omega [Image: see text] We report a selective and sensitive nanosensor probe based on polyethylenimine (PEI)-capped downconverting nanophosphors β-NaYF(4):Gd(3+),Tb(3+)@PEI for the detection of 2,4,6-trinitrotoluene (TNT), both in water and buffer media. These downconverting phosphors were synthesized via a hydrothermal route and are known to show excellent chemical, thermal, and photostability. They emit sharp emission peaks centered at ∼488, 544, 584, and 619 nm, among which the peak at ∼544 nm was remarkably quenched (∼90%) by the addition of TNT without giving any new emission peak. The sensing mechanism is based on the formation of a Meisenheimer complex between the electron-rich amine-functionalized β-NaYF(4):Gd(3+),Tb(3+) nanophosphors and electron-deficient TNT molecule, which was prominently visualized by the change in the color of the solution from whitish to brownish yellow, enabling visual detection, followed by luminescence resonance energy transfer between the nanophosphors and the complex. A linear range for TNT detection was obtained from 0.1 to 300 μM with a limit of detection as low as 119.9 nM. This method displayed excellent selectivity toward TNT over other nitroaromatic compounds, which had no influence on the detection. Moreover, various other classes of analytes, viz., amino acids, pesticides, and sugars, did not quench the luminescence intensity of the nanophosphors. This developed nanosensor probe possesses high, stable fluorescence brightness and capability for the selective and sensitive on-site recognition of TNT molecules in aqueous media, avoiding complicated strategies and instruments. Thus, this work promises to pave ways to many applications in the detection of ultratrace analytes. American Chemical Society 2019-02-26 /pmc/articles/PMC6648544/ /pubmed/31459633 http://dx.doi.org/10.1021/acsomega.8b03491 Text en Copyright © 2019 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Malik, Monika
Padhye, Preeti
Poddar, Pankaj
Downconversion Luminescence-Based Nanosensor for Label-Free Detection of Explosives
title Downconversion Luminescence-Based Nanosensor for Label-Free Detection of Explosives
title_full Downconversion Luminescence-Based Nanosensor for Label-Free Detection of Explosives
title_fullStr Downconversion Luminescence-Based Nanosensor for Label-Free Detection of Explosives
title_full_unstemmed Downconversion Luminescence-Based Nanosensor for Label-Free Detection of Explosives
title_short Downconversion Luminescence-Based Nanosensor for Label-Free Detection of Explosives
title_sort downconversion luminescence-based nanosensor for label-free detection of explosives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648544/
https://www.ncbi.nlm.nih.gov/pubmed/31459633
http://dx.doi.org/10.1021/acsomega.8b03491
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