BCl(3)-Mediated C–N, C–S, and C–O Bond Formation of Imidazo[1,2-a]pyridine Benzylic Ethers

[Image: see text] An efficient BCl(3)-mediated reaction of imidazo[1,2-a]pyridines has been developed for the C–N, C–S, and C–O bond formation. The salient features of this method correspond to the substitution of different nucleophiles via in situ unconventional debenzylation. The developed process...

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Autores principales: Singh, Davinder, Kumar, Gulshan, Dheer, Divya, Jyoti, Kushwaha, Manoj, Ahmed, Qazi Naveed, Shankar, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648736/
https://www.ncbi.nlm.nih.gov/pubmed/31459646
http://dx.doi.org/10.1021/acsomega.9b00035
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author Singh, Davinder
Kumar, Gulshan
Dheer, Divya
Jyoti,
Kushwaha, Manoj
Ahmed, Qazi Naveed
Shankar, Ravi
author_facet Singh, Davinder
Kumar, Gulshan
Dheer, Divya
Jyoti,
Kushwaha, Manoj
Ahmed, Qazi Naveed
Shankar, Ravi
author_sort Singh, Davinder
collection PubMed
description [Image: see text] An efficient BCl(3)-mediated reaction of imidazo[1,2-a]pyridines has been developed for the C–N, C–S, and C–O bond formation. The salient features of this method correspond to the substitution of different nucleophiles via in situ unconventional debenzylation. The developed process is applicable for the synthesis of a wide variety of ((3-amino/thio/alkoxy)-methyl)-imidazo[1,2-a]pyridines.
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spelling pubmed-66487362019-08-27 BCl(3)-Mediated C–N, C–S, and C–O Bond Formation of Imidazo[1,2-a]pyridine Benzylic Ethers Singh, Davinder Kumar, Gulshan Dheer, Divya Jyoti, Kushwaha, Manoj Ahmed, Qazi Naveed Shankar, Ravi ACS Omega [Image: see text] An efficient BCl(3)-mediated reaction of imidazo[1,2-a]pyridines has been developed for the C–N, C–S, and C–O bond formation. The salient features of this method correspond to the substitution of different nucleophiles via in situ unconventional debenzylation. The developed process is applicable for the synthesis of a wide variety of ((3-amino/thio/alkoxy)-methyl)-imidazo[1,2-a]pyridines. American Chemical Society 2019-03-01 /pmc/articles/PMC6648736/ /pubmed/31459646 http://dx.doi.org/10.1021/acsomega.9b00035 Text en Copyright © 2019 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Singh, Davinder
Kumar, Gulshan
Dheer, Divya
Jyoti,
Kushwaha, Manoj
Ahmed, Qazi Naveed
Shankar, Ravi
BCl(3)-Mediated C–N, C–S, and C–O Bond Formation of Imidazo[1,2-a]pyridine Benzylic Ethers
title BCl(3)-Mediated C–N, C–S, and C–O Bond Formation of Imidazo[1,2-a]pyridine Benzylic Ethers
title_full BCl(3)-Mediated C–N, C–S, and C–O Bond Formation of Imidazo[1,2-a]pyridine Benzylic Ethers
title_fullStr BCl(3)-Mediated C–N, C–S, and C–O Bond Formation of Imidazo[1,2-a]pyridine Benzylic Ethers
title_full_unstemmed BCl(3)-Mediated C–N, C–S, and C–O Bond Formation of Imidazo[1,2-a]pyridine Benzylic Ethers
title_short BCl(3)-Mediated C–N, C–S, and C–O Bond Formation of Imidazo[1,2-a]pyridine Benzylic Ethers
title_sort bcl(3)-mediated c–n, c–s, and c–o bond formation of imidazo[1,2-a]pyridine benzylic ethers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648736/
https://www.ncbi.nlm.nih.gov/pubmed/31459646
http://dx.doi.org/10.1021/acsomega.9b00035
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