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Acute depletion of CTCF directly affects MYC regulation through loss of enhancer–promoter looping

Numerous pieces of evidence support the complex, 3D spatial organization of the genome dictates gene expression. CTCF is essential to define topologically associated domain boundaries and to facilitate the formation of insulated chromatin loop structures. To understand CTCF’s direct role in global t...

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Detalles Bibliográficos
Autores principales:	Hyle, Judith, Zhang, Yang, Wright, Shaela, Xu, Beisi, Shao, Ying, Easton, John, Tian, Liqing, Feng, Ruopeng, Xu, Peng, Li, Chunliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6648894/ https://www.ncbi.nlm.nih.gov/pubmed/31127282 http://dx.doi.org/10.1093/nar/gkz462

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