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The SOXE transcription factors—SOX8, SOX9 and SOX10—share a bi-partite transactivation mechanism

SOX8, SOX9 and SOX10 compose the SOXE transcription factor group. They govern cell fate and differentiation in many lineages, and mutations impairing their activity cause severe diseases, including campomelic dysplasia (SOX9), sex determination disorders (SOX8 and SOX9) and Waardenburg-Shah syndrome...

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Detalles Bibliográficos
Autores principales: Haseeb, Abdul, Lefebvre, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649842/
https://www.ncbi.nlm.nih.gov/pubmed/31194875
http://dx.doi.org/10.1093/nar/gkz523