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The SOXE transcription factors—SOX8, SOX9 and SOX10—share a bi-partite transactivation mechanism
SOX8, SOX9 and SOX10 compose the SOXE transcription factor group. They govern cell fate and differentiation in many lineages, and mutations impairing their activity cause severe diseases, including campomelic dysplasia (SOX9), sex determination disorders (SOX8 and SOX9) and Waardenburg-Shah syndrome...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649842/ https://www.ncbi.nlm.nih.gov/pubmed/31194875 http://dx.doi.org/10.1093/nar/gkz523 |