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Interleukin-6 does not upregulate pro-inflammatory cytokine expression in an ex vivo model of giant cell arteritis

OBJECTIVE: The aim of this study was to examine the pro-inflammatory effects of IL-6 in ex vivo temporal artery explant cultures. METHODS: Patients meeting 1990 ACR classification criteria for GCA were prospectively recruited. Temporal artery biopsies were obtained and temporal artery explants cultu...

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Detalles Bibliográficos
Autores principales: O’Neill, Lorraine, McCormick, Jennifer, Gao, Wei, Veale, Douglas J, McCarthy, Geraldine M, Murphy, Conor C, Fearon, Ursula, Molloy, Eamonn S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649906/
https://www.ncbi.nlm.nih.gov/pubmed/31431999
http://dx.doi.org/10.1093/rap/rkz011