Cargando…
A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity
BMP/SMAD signaling is a crucial regulator of intestinal differentiation(1–4). However, the molecular underpinnings of the BMP pathway in this context are unknown. Here, we characterize the mechanism by which BMP/SMAD signaling drives enterocyte differentiation. We establish that the transcription fa...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650150/ https://www.ncbi.nlm.nih.gov/pubmed/30988513 http://dx.doi.org/10.1038/s41588-019-0384-0 |