Sensitivity and specificity evaluation of multiple neurodegenerative proteins for Creutzfeldt-Jakob disease diagnosis using a deep-learning approach

The diagnosis of sporadic Creutzfeldt-Jakob disease (sCJD) can only be confirmed by abnormal protease-resistant prion protein accumulation in post-mortem brain tissue. The relationships between sCJD and cerebrospinal fluid (CSF) proteins such as 14–3-3, tau, and α-synuclein (a-syn) have been investi...

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Detalles Bibliográficos
Autores principales: Lee, Sol Moe, Hyeon, Jae Wook, Kim, Soo-Jin, Kim, Heebal, Noh, Ran, Kim, Seonghan, Lee, Yeong Seon, Kim, Su Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650195/
https://www.ncbi.nlm.nih.gov/pubmed/31306078
http://dx.doi.org/10.1080/19336896.2019.1639482

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