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Thymic regulatory T cells arise via two distinct developmental programs

The developmental programs that generate a broad repertoire of regulatory T cells (T(reg) cells) able to respond to both self antigens and non–self antigens remain unclear. Here we found that mature T(reg) cells were generated through two distinct developmental programs involving CD25(+) T(reg) cell...

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Detalles Bibliográficos
Autores principales:	Owen, David L., Mahmud, Shawn A., Sjaastad, Louisa E., Williams, Jason B., Spanier, Justin A., Simeonov, Dimitre R., Ruscher, Roland, Huang, Weishan, Proekt, Irina, Miller, Corey N., Hekim, Can, Jeschke, Jonathan C., Aggarwal, Praful, Broeckel, Ulrich, LaRue, Rebecca S., Henzler, Christine M., Alegre, Maria-Luisa, Anderson, Mark S., August, Avery, Marson, Alexander, Zheng, Ye, Williams, Calvin B., Farrar, Michael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650268/ https://www.ncbi.nlm.nih.gov/pubmed/30643267 http://dx.doi.org/10.1038/s41590-018-0289-6

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