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Nucleus Accumbens Modulation in Reward and Aversion

The nucleus accumbens (NAc) is a key node of the brain’s circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors. It is subject to modulation by a broad array of inp...

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Autores principales: Klawonn, Anna M., Malenka, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650377/
https://www.ncbi.nlm.nih.gov/pubmed/30674650
http://dx.doi.org/10.1101/sqb.2018.83.037457
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author Klawonn, Anna M.
Malenka, Robert C.
author_facet Klawonn, Anna M.
Malenka, Robert C.
author_sort Klawonn, Anna M.
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description The nucleus accumbens (NAc) is a key node of the brain’s circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors. It is subject to modulation by a broad array of inputs that influence NAc activity in complex ways that are still poorly understood. Here, we briefly review current knowledge about the behavioral consequences of NAc modulation, focusing on recent studies that use novel techniques developed and implemented over the last decade.
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spelling pubmed-66503772019-09-10 Nucleus Accumbens Modulation in Reward and Aversion Klawonn, Anna M. Malenka, Robert C. Cold Spring Harb Symp Quant Biol Article The nucleus accumbens (NAc) is a key node of the brain’s circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors. It is subject to modulation by a broad array of inputs that influence NAc activity in complex ways that are still poorly understood. Here, we briefly review current knowledge about the behavioral consequences of NAc modulation, focusing on recent studies that use novel techniques developed and implemented over the last decade. 2019-01-23 2018 /pmc/articles/PMC6650377/ /pubmed/30674650 http://dx.doi.org/10.1101/sqb.2018.83.037457 Text en This article is distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/) , which permits reuse and redistribution, except for commercial purposes, provided that the original author and source are credited.
spellingShingle Article
Klawonn, Anna M.
Malenka, Robert C.
Nucleus Accumbens Modulation in Reward and Aversion
title Nucleus Accumbens Modulation in Reward and Aversion
title_full Nucleus Accumbens Modulation in Reward and Aversion
title_fullStr Nucleus Accumbens Modulation in Reward and Aversion
title_full_unstemmed Nucleus Accumbens Modulation in Reward and Aversion
title_short Nucleus Accumbens Modulation in Reward and Aversion
title_sort nucleus accumbens modulation in reward and aversion
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650377/
https://www.ncbi.nlm.nih.gov/pubmed/30674650
http://dx.doi.org/10.1101/sqb.2018.83.037457
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