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Nucleus Accumbens Modulation in Reward and Aversion
The nucleus accumbens (NAc) is a key node of the brain’s circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors. It is subject to modulation by a broad array of inp...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650377/ https://www.ncbi.nlm.nih.gov/pubmed/30674650 http://dx.doi.org/10.1101/sqb.2018.83.037457 |
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author | Klawonn, Anna M. Malenka, Robert C. |
author_facet | Klawonn, Anna M. Malenka, Robert C. |
author_sort | Klawonn, Anna M. |
collection | PubMed |
description | The nucleus accumbens (NAc) is a key node of the brain’s circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors. It is subject to modulation by a broad array of inputs that influence NAc activity in complex ways that are still poorly understood. Here, we briefly review current knowledge about the behavioral consequences of NAc modulation, focusing on recent studies that use novel techniques developed and implemented over the last decade. |
format | Online Article Text |
id | pubmed-6650377 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
record_format | MEDLINE/PubMed |
spelling | pubmed-66503772019-09-10 Nucleus Accumbens Modulation in Reward and Aversion Klawonn, Anna M. Malenka, Robert C. Cold Spring Harb Symp Quant Biol Article The nucleus accumbens (NAc) is a key node of the brain’s circuitry that is responsible for translating motivation into action. It has been implicated in playing critical roles in virtually all forms of adaptive and pathological motivated behaviors. It is subject to modulation by a broad array of inputs that influence NAc activity in complex ways that are still poorly understood. Here, we briefly review current knowledge about the behavioral consequences of NAc modulation, focusing on recent studies that use novel techniques developed and implemented over the last decade. 2019-01-23 2018 /pmc/articles/PMC6650377/ /pubmed/30674650 http://dx.doi.org/10.1101/sqb.2018.83.037457 Text en This article is distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/) , which permits reuse and redistribution, except for commercial purposes, provided that the original author and source are credited. |
spellingShingle | Article Klawonn, Anna M. Malenka, Robert C. Nucleus Accumbens Modulation in Reward and Aversion |
title | Nucleus Accumbens Modulation in Reward and Aversion |
title_full | Nucleus Accumbens Modulation in Reward and Aversion |
title_fullStr | Nucleus Accumbens Modulation in Reward and Aversion |
title_full_unstemmed | Nucleus Accumbens Modulation in Reward and Aversion |
title_short | Nucleus Accumbens Modulation in Reward and Aversion |
title_sort | nucleus accumbens modulation in reward and aversion |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650377/ https://www.ncbi.nlm.nih.gov/pubmed/30674650 http://dx.doi.org/10.1101/sqb.2018.83.037457 |
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