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Evolutionary history of teleost intron-containing and intron-less rhodopsin genes
Recent progress in whole genome sequencing has revealed that animals have various kinds of opsin genes for photoreception. Among them, most opsin genes have introns in their coding regions. However, it has been known for a long time that teleost retinas express intron-less rhodopsin genes, which are...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650399/ https://www.ncbi.nlm.nih.gov/pubmed/31337799 http://dx.doi.org/10.1038/s41598-019-47028-4 |
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author | Fujiyabu, Chihiro Sato, Keita Utari, Ni Made Laksmi Ohuchi, Hideyo Shichida, Yoshinori Yamashita, Takahiro |
author_facet | Fujiyabu, Chihiro Sato, Keita Utari, Ni Made Laksmi Ohuchi, Hideyo Shichida, Yoshinori Yamashita, Takahiro |
author_sort | Fujiyabu, Chihiro |
collection | PubMed |
description | Recent progress in whole genome sequencing has revealed that animals have various kinds of opsin genes for photoreception. Among them, most opsin genes have introns in their coding regions. However, it has been known for a long time that teleost retinas express intron-less rhodopsin genes, which are presumed to have been formed by retroduplication from an ancestral intron-containing rhodopsin gene. In addition, teleosts have an intron-containing rhodopsin gene (exo-rhodopsin) exclusively for pineal photoreception. In this study, to unravel the evolutionary origin of the two teleost rhodopsin genes, we analyzed the rhodopsin genes of non-teleost fishes in the Actinopterygii. The phylogenetic analysis of full-length sequences of bichir, sturgeon and gar rhodopsins revealed that retroduplication of the rhodopsin gene occurred after branching of the bichir lineage. In addition, analysis of the tissue distribution and the molecular properties of bichir, sturgeon and gar rhodopsins showed that the abundant and exclusive expression of intron-containing rhodopsin in the pineal gland and the short lifetime of its meta II intermediate, which leads to optimization for pineal photoreception, were achieved after branching of the gar lineage. Based on these results, we propose a stepwise evolutionary model of teleost intron-containing and intron-less rhodopsin genes. |
format | Online Article Text |
id | pubmed-6650399 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-66503992019-07-29 Evolutionary history of teleost intron-containing and intron-less rhodopsin genes Fujiyabu, Chihiro Sato, Keita Utari, Ni Made Laksmi Ohuchi, Hideyo Shichida, Yoshinori Yamashita, Takahiro Sci Rep Article Recent progress in whole genome sequencing has revealed that animals have various kinds of opsin genes for photoreception. Among them, most opsin genes have introns in their coding regions. However, it has been known for a long time that teleost retinas express intron-less rhodopsin genes, which are presumed to have been formed by retroduplication from an ancestral intron-containing rhodopsin gene. In addition, teleosts have an intron-containing rhodopsin gene (exo-rhodopsin) exclusively for pineal photoreception. In this study, to unravel the evolutionary origin of the two teleost rhodopsin genes, we analyzed the rhodopsin genes of non-teleost fishes in the Actinopterygii. The phylogenetic analysis of full-length sequences of bichir, sturgeon and gar rhodopsins revealed that retroduplication of the rhodopsin gene occurred after branching of the bichir lineage. In addition, analysis of the tissue distribution and the molecular properties of bichir, sturgeon and gar rhodopsins showed that the abundant and exclusive expression of intron-containing rhodopsin in the pineal gland and the short lifetime of its meta II intermediate, which leads to optimization for pineal photoreception, were achieved after branching of the gar lineage. Based on these results, we propose a stepwise evolutionary model of teleost intron-containing and intron-less rhodopsin genes. Nature Publishing Group UK 2019-07-23 /pmc/articles/PMC6650399/ /pubmed/31337799 http://dx.doi.org/10.1038/s41598-019-47028-4 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Fujiyabu, Chihiro Sato, Keita Utari, Ni Made Laksmi Ohuchi, Hideyo Shichida, Yoshinori Yamashita, Takahiro Evolutionary history of teleost intron-containing and intron-less rhodopsin genes |
title | Evolutionary history of teleost intron-containing and intron-less rhodopsin genes |
title_full | Evolutionary history of teleost intron-containing and intron-less rhodopsin genes |
title_fullStr | Evolutionary history of teleost intron-containing and intron-less rhodopsin genes |
title_full_unstemmed | Evolutionary history of teleost intron-containing and intron-less rhodopsin genes |
title_short | Evolutionary history of teleost intron-containing and intron-less rhodopsin genes |
title_sort | evolutionary history of teleost intron-containing and intron-less rhodopsin genes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650399/ https://www.ncbi.nlm.nih.gov/pubmed/31337799 http://dx.doi.org/10.1038/s41598-019-47028-4 |
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