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Biochemical characterisation of fumarase C from a unicellular cyanobacterium demonstrating its substrate affinity, altered by an amino acid substitution

The tricarboxylic acid cycle produces NADH for oxidative phosphorylation and fumarase [EC 4.2.1.2] is a critical enzyme in this cycle, catalysing the reversible conversion of fumarate and l-malate. Fumarase is applied to industrial l-malate production as a biocatalyst. l-malate is used in a wide ran...

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Detalles Bibliográficos
Autores principales: Katayama, Noriaki, Takeya, Masahiro, Osanai, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650407/
https://www.ncbi.nlm.nih.gov/pubmed/31337820
http://dx.doi.org/10.1038/s41598-019-47025-7

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