Cargando…

Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism

Plasmodium parasites are obligate intracellular protozoa and causative agents of malaria, responsible for half a million deaths each year. The lifecycle progression of the parasite is reliant on cell motility, a process driven by myosin A, an unconventional single-headed class XIV molecular motor. H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Robert-Paganin, Julien, Robblee, James P., Auguin, Daniel, Blake, Thomas C. A., Bookwalter, Carol S., Krementsova, Elena B., Moussaoui, Dihia, Previs, Michael J., Jousset, Guillaume, Baum, Jake, Trybus, Kathleen M., Houdusse, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650474/ https://www.ncbi.nlm.nih.gov/pubmed/31337750 http://dx.doi.org/10.1038/s41467-019-11120-0

Ejemplares similares

Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets
por: Moussaoui, Dihia, et al.
Publicado: (2020)

Mechanism of small molecule inhibition of Plasmodium falciparum myosin A informs antimalarial drug design
por: Moussaoui, Dihia, et al.
Publicado: (2023)

Reconstitution of the core of the malaria parasite glideosome with recombinant Plasmodium class XIV myosin A and Plasmodium actin
por: Bookwalter, Carol S., et al.
Publicado: (2017)

Cryo-EM structure of the folded-back state of human β-cardiac myosin(*)
por: Grinzato, Alessandro, et al.
Publicado: (2023)

Cryo-EM structure of the folded-back state of human β-cardiac myosin
por: Grinzato, Alessandro, et al.
Publicado: (2023)

Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition
por: Robert-Paganin, Julien, et al.
Publicado: (2018)

A single-headed fission yeast myosin V transports actin in a tropomyosin-dependent manner
por: Tang, Qing, et al.
Publicado: (2016)

The actomyosin interface contains an evolutionary conserved core and an ancillary interface involved in specificity
por: Robert-Paganin, Julien, et al.
Publicado: (2021)

Two single-headed myosin V motors bound to a tetrameric adapter protein form a processive complex
por: Krementsova, Elena B., et al.
Publicado: (2011)

Single molecule reconstitution of mRNA transport by a class V myosin
por: Sladewski, Thomas E., et al.
Publicado: (2013)

Myosin V: regulation by calcium, calmodulin, and the tail domain
por: Krementsov, Dimitry N., et al.
Publicado: (2004)

Myosin 7 and its adaptors link cadherins to actin
por: Yu, I-Mei, et al.
Publicado: (2017)

Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil
por: Planelles-Herrero, Vicente J., et al.
Publicado: (2017)

Actomyosin forces and the energetics of red blood cell invasion by the malaria parasite Plasmodium falciparum
por: Blake, Thomas C. A., et al.
Publicado: (2020)

Tropomyosin isoforms bias actin track selection by vertebrate myosin Va
por: Sckolnick, Maria, et al.
Publicado: (2016)

Myosin V exhibits a high duty cycle and large unitary displacement
por: Moore, Jeffrey R., et al.
Publicado: (2001)

Fission yeast tropomyosin specifies directed transport of myosin-V along actin cables
por: Clayton, Joseph E., et al.
Publicado: (2014)

Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complex
por: Sladewski, Thomas E, et al.
Publicado: (2018)

How myosin VI traps its off-state, is activated and dimerizes
por: Canon, Louise, et al.
Publicado: (2023)

Revealing the mechanism of how cardiac myosin-binding protein C N-terminal fragments sensitize thin filaments for myosin binding
por: Inchingolo, Alessio V., et al.
Publicado: (2019)

Identification and characterisation of a phospholipid scramblase in the malaria parasite Plasmodium falciparum
por: Haase, Silvia, et al.
Publicado: (2021)

Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle
por: Nelson, Shane, et al.
Publicado: (2023)

Allosteric Communication in Myosin V: From Small Conformational Changes to Large Directed Movements
por: Cecchini, M., et al.
Publicado: (2008)

VASP-mediated actin dynamics activate and recruit a filopodia myosin
por: Arthur, Ashley L, et al.
Publicado: (2021)

Systematic analysis of Plasmodium myosins reveals differential expression, localisation, and function in invasive and proliferative parasite stages
por: Wall, Richard J., et al.
Publicado: (2019)

Peptide Probes for Plasmodium falciparum MyoA Tail Interacting Protein (MTIP): Exploring the Druggability of the Malaria Parasite Motor Complex
por: Saunders, Charlie N., et al.
Publicado: (2020)

Live-cell fluorescence imaging of microgametogenesis in the human malaria parasite Plasmodium falciparum
por: Yahiya, Sabrina, et al.
Publicado: (2022)

Multiple kinesins induce tension for smooth cargo transport
por: Tjioe, Marco, et al.
Publicado: (2019)

Visualization of Head–Head Interactions in the Inhibited State of Smooth Muscle Myosin
por: Wendt, Thomas, et al.
Publicado: (1999)

Radial spoke protein 9 is necessary for axoneme assembly in Plasmodium but not in trypanosomatid parasites
por: Ramakrishnan, Chandra, et al.
Publicado: (2023)

A Perspective for Ménière’s Disease: In Silico Investigations of Dexamethasone as a Direct Modulator of AQP2
por: Mom, Robin, et al.
Publicado: (2022)

Nanosurfer assay dissects β-cardiac myosin and cardiac myosin-binding protein C interactions
por: Touma, Anja M., et al.
Publicado: (2022)

Genetic impairment of parasite myosin motors uncovers the contribution of host cell membrane dynamics to Toxoplasma invasion forces
por: Bichet, Marion, et al.
Publicado: (2016)

Cardiac Myosin Filaments are Maintained by Stochastic Protein Replacement
por: Wood, Neil B., et al.
Publicado: (2022)

Drosophila melanogaster Myosin-18 Represents a Highly Divergent Motor with Actin Tethering Properties
por: Guzik-Lendrum, Stephanie, et al.
Publicado: (2011)

The carboxyl-terminal isoforms of smooth muscle myosin heavy chain determine thick filament assembly properties
por: Rovner, Arthur S., et al.
Publicado: (2002)

Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction coupling
por: Previs, Michael J., et al.
Publicado: (2015)

Reassessing the mechanics of parasite motility and host-cell invasion
por: Tardieux, Isabelle, et al.
Publicado: (2016)

Force Generation by Membrane-Associated Myosin-I
por: Pyrpassopoulos, Serapion, et al.
Publicado: (2016)

Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum
por: Wilson, Danny W, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_v9eei1iermrfmgjcculi6n9hro