Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis

The Muc-1 oncoprotein is a tumor-associated mucin often overexpressed in pancreatic cancer. We report that knockout of Muc-1 reduced the degree of pancreatic inflammation that resulted from infection with Coxsackievirus B3 (CVB3) in a mouse model. CVB3-infected Muc-1-deficient (Muc-1(KO)) mice had s...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiang, Clemens, Dahn L., Grunkemeyer, James A., Price, Jeffrey D., O’Connell, Kelly, Chapman, Nora M., Storz, Peter, Wen, Haitao, Cox, Jesse L., Reid, Whitney L., Hollingsworth, Michael A., Thayer, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650496/
https://www.ncbi.nlm.nih.gov/pubmed/31337812
http://dx.doi.org/10.1038/s41598-019-46933-y

Ejemplares similares

Ejemplares similares