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High-Resolution Pulse Oximetry and Titration of a Mandibular Advancement Device for Obstructive Sleep Apnea

Background: To determine whether utilizing high-resolution pulse oximetry is a viable method for evaluating the successful titration of oral appliances for the treatment of obstructive sleep apnea (OSA) patients. Methods: Of 136 consecutive potentially eligible OSA patients, 133 were fitted with man...

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Autores principales: Metz, James E., Attarian, Hrayr P., Harrison, Mickey C., Blank, James E., Takacs, Christopher M., Smith, Dale L., Gozal, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650535/
https://www.ncbi.nlm.nih.gov/pubmed/31379712
http://dx.doi.org/10.3389/fneur.2019.00757
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author Metz, James E.
Attarian, Hrayr P.
Harrison, Mickey C.
Blank, James E.
Takacs, Christopher M.
Smith, Dale L.
Gozal, David
author_facet Metz, James E.
Attarian, Hrayr P.
Harrison, Mickey C.
Blank, James E.
Takacs, Christopher M.
Smith, Dale L.
Gozal, David
author_sort Metz, James E.
collection PubMed
description Background: To determine whether utilizing high-resolution pulse oximetry is a viable method for evaluating the successful titration of oral appliances for the treatment of obstructive sleep apnea (OSA) patients. Methods: Of 136 consecutive potentially eligible OSA patients, 133 were fitted with mandibular advancement devices (MADs), and 101 completed all phases of treatment. The vertical and horizontal dimensions of the appliances were adjusted based on three-nights with a high-resolution pulse oximeter during sleep and associated software after each adjustment. Results: Significant improvements in OSA severity were apparent in patients at all disease severity levels. High-resolution pulse oximetry provided reliable guidance in the titration process of mandibular advancement therapy. In 67 subjects (66.3%), a respiratory event index of <5 events/hour was achieved. Conclusions: OSA can be effectively treated with a MAD at any severity level, and high-resolution pulse oximetry provides critical information to guide oral appliance titration.
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spelling pubmed-66505352019-08-02 High-Resolution Pulse Oximetry and Titration of a Mandibular Advancement Device for Obstructive Sleep Apnea Metz, James E. Attarian, Hrayr P. Harrison, Mickey C. Blank, James E. Takacs, Christopher M. Smith, Dale L. Gozal, David Front Neurol Neurology Background: To determine whether utilizing high-resolution pulse oximetry is a viable method for evaluating the successful titration of oral appliances for the treatment of obstructive sleep apnea (OSA) patients. Methods: Of 136 consecutive potentially eligible OSA patients, 133 were fitted with mandibular advancement devices (MADs), and 101 completed all phases of treatment. The vertical and horizontal dimensions of the appliances were adjusted based on three-nights with a high-resolution pulse oximeter during sleep and associated software after each adjustment. Results: Significant improvements in OSA severity were apparent in patients at all disease severity levels. High-resolution pulse oximetry provided reliable guidance in the titration process of mandibular advancement therapy. In 67 subjects (66.3%), a respiratory event index of <5 events/hour was achieved. Conclusions: OSA can be effectively treated with a MAD at any severity level, and high-resolution pulse oximetry provides critical information to guide oral appliance titration. Frontiers Media S.A. 2019-07-17 /pmc/articles/PMC6650535/ /pubmed/31379712 http://dx.doi.org/10.3389/fneur.2019.00757 Text en Copyright © 2019 Metz, Attarian, Harrison, Blank, Takacs, Smith and Gozal. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Metz, James E.
Attarian, Hrayr P.
Harrison, Mickey C.
Blank, James E.
Takacs, Christopher M.
Smith, Dale L.
Gozal, David
High-Resolution Pulse Oximetry and Titration of a Mandibular Advancement Device for Obstructive Sleep Apnea
title High-Resolution Pulse Oximetry and Titration of a Mandibular Advancement Device for Obstructive Sleep Apnea
title_full High-Resolution Pulse Oximetry and Titration of a Mandibular Advancement Device for Obstructive Sleep Apnea
title_fullStr High-Resolution Pulse Oximetry and Titration of a Mandibular Advancement Device for Obstructive Sleep Apnea
title_full_unstemmed High-Resolution Pulse Oximetry and Titration of a Mandibular Advancement Device for Obstructive Sleep Apnea
title_short High-Resolution Pulse Oximetry and Titration of a Mandibular Advancement Device for Obstructive Sleep Apnea
title_sort high-resolution pulse oximetry and titration of a mandibular advancement device for obstructive sleep apnea
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650535/
https://www.ncbi.nlm.nih.gov/pubmed/31379712
http://dx.doi.org/10.3389/fneur.2019.00757
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