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Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia: an open-label, observational, phase 4 study

BACKGROUND: The efficacy and effectiveness of the pandemic H1N1 (pH1N1) component in live attenuated influenza vaccine (LAIV) is poor. The reasons for this paucity are unclear but could be due to impaired replicative fitness of pH1N1 A/California/07/2009-like (Cal09) strains. We assessed whether an...

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Detalles Bibliográficos
Autores principales:	Lindsey, Benjamin B, Jagne, Ya Jankey, Armitage, Edwin P, Singanayagam, Anika, Sallah, Hadijatou J, Drammeh, Sainabou, Senghore, Elina, Mohammed, Nuredin I, Jeffries, David, Höschler, Katja, Tregoning, John S, Meijer, Adam, Clarke, Ed, Dong, Tao, Barclay, Wendy, Kampmann, Beate, de Silva, Thushan I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650545/ https://www.ncbi.nlm.nih.gov/pubmed/31235405 http://dx.doi.org/10.1016/S2213-2600(19)30086-4

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