Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP

Subversion of endoplasmic reticulum (ER) function is a feature shared by multiple intracellular bacteria and viruses, and in many cases this disruption of cellular function activates pathways of the unfolded protein response (UPR). In the case of infection with Brucella abortus, the etiologic agent...

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Detalles Bibliográficos
Autores principales: Byndloss, Mariana X., Tsai, April Y., Walker, Gregory T., Miller, Cheryl N., Young, Briana M., English, Bevin C., Seyffert, Núbia, Kerrinnes, Tobias, de Jong, Maarten F., Atluri, Vidya L., Winter, Maria G., Celli, Jean, Tsolis, Renée M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650558/
https://www.ncbi.nlm.nih.gov/pubmed/31337727
http://dx.doi.org/10.1128/mBio.01538-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650558/
https://www.ncbi.nlm.nih.gov/pubmed/31337727
http://dx.doi.org/10.1128/mBio.01538-19

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