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The Interaction of Klebsiella pneumoniae With Lipid Rafts-Associated Cholesterol Increases Macrophage-Mediated Phagocytosis Due to Down Regulation of the Capsule Polysaccharide
Klebsiella pneumoniae successfully colonizes host tissues by recognizing and interacting with cholesterol present on membrane-associated lipid rafts. In this study, we evaluated the role of cholesterol in the expression of capsule polysaccharide genes of K. pneumoniae and its implication in resistan...
Autores principales: | Ares, Miguel A., Sansabas, Alejandro, Rodríguez-Valverde, Diana, Siqueiros-Cendón, Tania, Rascón-Cruz, Quintín, Rosales-Reyes, Roberto, Jarillo-Quijada, Ma. Dolores, Alcántar-Curiel, María D., Cedillo, María L., Torres, Javier, Girón, Jorge A., De la Cruz, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650577/ https://www.ncbi.nlm.nih.gov/pubmed/31380298 http://dx.doi.org/10.3389/fcimb.2019.00255 |
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