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Accurate Quantification and Characterization of Adeno-Associated Viral Vectors

One of the main challenges in the gene therapy viral vector development is to establish an optimized process for its large scale production. This requires optimization for upstream and downstream processes as well as methods that enable the step-by step analytical characterization of the virus, the...

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Detalles Bibliográficos
Autores principales: Dobnik, David, Kogovšek, Polona, Jakomin, Tjaša, Košir, Nejc, Tušek Žnidarič, Magda, Leskovec, Maja, Kaminsky, Stephen M., Mostrom, Janet, Lee, Hyunmi, Ravnikar, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650692/
https://www.ncbi.nlm.nih.gov/pubmed/31379763
http://dx.doi.org/10.3389/fmicb.2019.01570