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Lnc-C/EBPβ Modulates Differentiation of MDSCs Through Downregulating IL4i1 With C/EBPβ LIP and WDR5
Myeloid-derived suppressor cells (MDSCs), which play an important role in tumor and inflammatory diseases, are divided into two subsets CD11b(+)Ly6C(hi)Ly6G(−) monocytic MDSC (Mo-MDSC) and CD11b(+)Ly6C(low/neg)Ly6G(+) polymorphonuclear MDSC (PMN-MDSC) with different immunosuppressive function. Howev...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650770/ https://www.ncbi.nlm.nih.gov/pubmed/31379854 http://dx.doi.org/10.3389/fimmu.2019.01661 |