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Lnc-C/EBPβ Modulates Differentiation of MDSCs Through Downregulating IL4i1 With C/EBPβ LIP and WDR5

Myeloid-derived suppressor cells (MDSCs), which play an important role in tumor and inflammatory diseases, are divided into two subsets CD11b(+)Ly6C(hi)Ly6G(−) monocytic MDSC (Mo-MDSC) and CD11b(+)Ly6C(low/neg)Ly6G(+) polymorphonuclear MDSC (PMN-MDSC) with different immunosuppressive function. Howev...

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Detalles Bibliográficos
Autores principales:	Gao, Yunhuan, Shang, Wencong, Zhang, Dan, Zhang, Shiwu, Zhang, Xipeng, Zhang, Yuan, Yang, Rongcun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650770/ https://www.ncbi.nlm.nih.gov/pubmed/31379854 http://dx.doi.org/10.3389/fimmu.2019.01661

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