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Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder

Autism Spectrum Disorder (ASD) is a developmental disorder characterized by social and communication deficits and repetitive behaviors. Children with ASD are also at a higher risk for developing overweight or obesity than children with typical development (TD). Childhood obesity has been associated...

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Autores principales: Dhaliwal, Khushmol K., Orsso, Camila E., Richard, Caroline, Haqq, Andrea M., Zwaigenbaum, Lonnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650879/
https://www.ncbi.nlm.nih.gov/pubmed/31277383
http://dx.doi.org/10.3390/ijms20133285
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author Dhaliwal, Khushmol K.
Orsso, Camila E.
Richard, Caroline
Haqq, Andrea M.
Zwaigenbaum, Lonnie
author_facet Dhaliwal, Khushmol K.
Orsso, Camila E.
Richard, Caroline
Haqq, Andrea M.
Zwaigenbaum, Lonnie
author_sort Dhaliwal, Khushmol K.
collection PubMed
description Autism Spectrum Disorder (ASD) is a developmental disorder characterized by social and communication deficits and repetitive behaviors. Children with ASD are also at a higher risk for developing overweight or obesity than children with typical development (TD). Childhood obesity has been associated with adverse health outcomes, including insulin resistance, diabetes, heart disease, and certain cancers. Importantly some key factors that play a mediating role in these higher rates of obesity include lifestyle factors and biological influences, as well as secondary comorbidities and medications. This review summarizes current knowledge about behavioral and lifestyle factors that could contribute to unhealthy weight gain in children with ASD, as well as the current state of knowledge of emerging risk factors such as the possible influence of sleep problems, the gut microbiome, endocrine influences and maternal metabolic disorders. We also discuss some of the clinical implications of these risk factors and areas for future research.
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spelling pubmed-66508792019-08-07 Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder Dhaliwal, Khushmol K. Orsso, Camila E. Richard, Caroline Haqq, Andrea M. Zwaigenbaum, Lonnie Int J Mol Sci Review Autism Spectrum Disorder (ASD) is a developmental disorder characterized by social and communication deficits and repetitive behaviors. Children with ASD are also at a higher risk for developing overweight or obesity than children with typical development (TD). Childhood obesity has been associated with adverse health outcomes, including insulin resistance, diabetes, heart disease, and certain cancers. Importantly some key factors that play a mediating role in these higher rates of obesity include lifestyle factors and biological influences, as well as secondary comorbidities and medications. This review summarizes current knowledge about behavioral and lifestyle factors that could contribute to unhealthy weight gain in children with ASD, as well as the current state of knowledge of emerging risk factors such as the possible influence of sleep problems, the gut microbiome, endocrine influences and maternal metabolic disorders. We also discuss some of the clinical implications of these risk factors and areas for future research. MDPI 2019-07-04 /pmc/articles/PMC6650879/ /pubmed/31277383 http://dx.doi.org/10.3390/ijms20133285 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Dhaliwal, Khushmol K.
Orsso, Camila E.
Richard, Caroline
Haqq, Andrea M.
Zwaigenbaum, Lonnie
Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder
title Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder
title_full Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder
title_fullStr Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder
title_full_unstemmed Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder
title_short Risk Factors for Unhealthy Weight Gain and Obesity among Children with Autism Spectrum Disorder
title_sort risk factors for unhealthy weight gain and obesity among children with autism spectrum disorder
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650879/
https://www.ncbi.nlm.nih.gov/pubmed/31277383
http://dx.doi.org/10.3390/ijms20133285
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